According to initial media reports, the aircraft, a Gulfstream G100 medical jet operated by a Canadian company, was carrying a patient along with five people, including the pilot.

The aircraft had departed Bermuda normally and was heading toward Boston, where the patient was due to be taken to a hospital for treatment. Reports said the patient was suffering from a complex medical condition.

The US Coast Guard has launched a search-and-rescue operation in waters off Massachusetts and near Nantucket. Multiple air and sea rescue teams are involved in efforts to locate the aircraft or any possible debris.

Reports said contact between the aircraft and the Federal Aviation Administration was lost at around 2 a.m. US time. The circumstances surrounding the disappearance remain unclear.

The incident has renewed public discussion about the Bermuda Triangle, an area of the Atlantic Ocean long associated with stories of aircraft and vessels mysteriously disappearing.

However, there is no evidence presented in the report that the Bermuda Triangle itself caused the aircraft to disappear. Authorities are continuing their search to determine what happened to the missing aircraft and its occupants.